Accelerating Breakthrough Therapies in People with T1D

The Breakthrough T1D Center of Excellence at the University of Michigan and Oregon Health & Science University bridges disciplines to develop safer, more effective treatments for T1D-related complications.

Our focus is on delivering swift clinical advancements to improve the lives of people living with Type 1 Diabetes.

Research and Innovation

The T1D Precision Medicine Platform is an advanced approach to treating cardio-renal complications by matching therapies to a patient’s specific needs.

Biomarkers and Pathways

Identifying and validating biomarkers and molecular pathways linked to T1D complications, enabling precise treatment matching.

Breakthrough Treatments

Conducting clinical trials with emerging therapies to assess their impact on reversing T1D complications.

Data Sharing and Collaboration

Sharing knowledge across platforms to foster further research and development in T1D treatment.

Meet the team

Our Investigators

Dedicated professionals committed to innovative diabetes research.

Matthias Kretzler, MD
University of Michigan

Passionate about advancing personalized treatments for Type 1 Diabetes and related complications.

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Rodica Pop-Busui, MD, PhD
Oregon Health & Science University

Expert in cardio-renal health, focusing on T1D patient outcomes and innovative care strategies.

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Wenjun Ju, PhD
University of Michigan

Strives to develop validated biomarkers in kidney precision medicine to improve patient care.

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Cathie Spino, ScD
University of Michigan

Advances patient therapeutic options by driving efficient clinical trial design using novel statistical methods.

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